There's a plastic ring around the top with large openings to let the screw heads seat against the metal. You will need to either remove the ring, or drill holes larger than the screw heads. Other than that, there's no reason why you can't.
As the first person to do this, I'm very happy with it. It took a few months to really break it in, so set you bass high in the beginning and then turn it down as the woofer loosens up.
My only complaint isn't volume its depth. You really can't get below 28Hz with that woofer in a free air installation. 28Hz is pretty deep though. I wish the B&O would let you adjust the subwoofer volume independently. Adding an amp just for a volume control is too much work IMO. If however you decide it isn't loud enough, then adding an amp is really easy. Buy something that can run 2 ohm and wire the woofer for parallel voice coils, rather than in series for the B&O, and you'll have no trouble making all the bass you want.
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